{"updated":"2026-05-07T12:01:46.354Z","license":"CC BY 4.0","strains":[{"slug":"andes-virus","name":"Andes","region":"South America","cfr":35,"cases":140,"human":true,"trend":[2,3,4,3,5,7,9,12,14,18,22,28],"description":"Andes orthohantavirus is the only hantavirus with documented person-to-person transmission, requiring close prolonged contact. It causes hantavirus pulmonary syndrome with case fatality typically 30–40%. Reservoir: long-tailed pygmy rice rat (Oligoryzomys longicaudatus).","reservoir":"Oligoryzomys longicaudatus (long-tailed pygmy rice rat)","syndrome":"HPS"},{"slug":"sin-nombre-virus","name":"Sin Nombre","region":"North America","cfr":36,"cases":42,"human":false,"trend":[2,2,3,3,4,4,5,6,7,8,10,12],"description":"Sin Nombre virus is the dominant strain in the southwestern United States, causing hantavirus pulmonary syndrome. Reservoir: deer mouse (Peromyscus maniculatus). Cases peak in spring after wet winters that increase rodent populations.","reservoir":"Peromyscus maniculatus (deer mouse)","syndrome":"HPS"},{"slug":"puumala-virus","name":"Puumala","region":"Northern Europe","cfr":0.5,"cases":580,"human":false,"trend":[12,18,24,32,45,68,84,102,128,156,182,210],"description":"Puumala virus causes a mild form of hemorrhagic fever with renal syndrome (nephropathia epidemica). Case fatality is below 1%. Reservoir: bank vole (Myodes glareolus). Most common hantavirus in Europe.","reservoir":"Myodes glareolus (bank vole)","syndrome":"HFRS"},{"slug":"hantaan-virus","name":"Hantaan","region":"East Asia","cfr":5,"cases":4280,"human":false,"trend":[180,210,260,310,380,450,520,610,720,840,960,1080],"description":"Hantaan virus is the prototype species, causing classic hemorrhagic fever with renal syndrome with up to ~10% case fatality in untreated cases. Reservoir: striped field mouse (Apodemus agrarius). Highest case loads occur seasonally in China and Korea.","reservoir":"Apodemus agrarius (striped field mouse)","syndrome":"HFRS"},{"slug":"seoul-virus","name":"Seoul","region":"Worldwide","cfr":1,"cases":120,"human":false,"trend":[8,10,9,11,12,14,13,15,16,18,19,21],"description":"Seoul virus has a global distribution due to its reservoir, the brown rat (Rattus norvegicus), which travels with human commerce. Causes a milder form of HFRS. Notable outbreaks have been linked to laboratory rats and pet rats.","reservoir":"Rattus norvegicus (brown rat)","syndrome":"HFRS"},{"slug":"dobrava-virus","name":"Dobrava","region":"Balkans","cfr":8,"cases":96,"human":false,"trend":[6,7,8,9,10,11,12,13,14,15,17,18],"description":"Dobrava-Belgrade virus causes the most severe form of HFRS in Europe with case fatality up to 12%. Reservoir: yellow-necked mouse (Apodemus flavicollis).","reservoir":"Apodemus flavicollis (yellow-necked mouse)","syndrome":"HFRS"},{"slug":"bayou-virus","name":"Bayou","region":"Southeastern United States","cfr":33,"cases":8,"human":false,"trend":[1,1,1,1,1,1,2,2,2,3,3,4],"description":"Bayou virus is the second most common cause of hantavirus pulmonary syndrome in the United States after Sin Nombre. Reservoir: rice rat (Oryzomys palustris) in the southeastern US.","reservoir":"Oryzomys palustris (rice rat)","syndrome":"HPS"}]}