Active outbreaks

Dutch-flagged expedition cruise with 147 aboard (88 passengers + 59 crew, 23 nationalities). Seven cases (two PCR-confirmed + five suspected) including three deaths. Andes hantavirus confirmed; vessel currently moored off Cabo Verde and headed for the Canary Islands. Affected states: Cabo Verde, Netherlands, Spain, South Africa, United Kingdom.

28 confirmed HPS cases reported year-to-date through MMWR week 23 of 2026. Cases concentrate in the Four Corners region (Sin Nombre virus) with smaller numbers from the Gulf Coast (Bayou virus).

Netherlands is among the five affected states per WHO DON599 (multiple Dutch nationals were aboard the MV Hondius). National IHR Focal Point coordinating contact tracing of disembarked passengers and evacuees.

Spain is among the five WHO-named affected states; the MV Hondius is heading to the Canary Islands for disembarkation. Spanish authorities preparing port-of-entry response and contact tracing.

Disembarked Dutch passenger admitted to a Johannesburg hospital where she died. South Africa NICD coordinating with WHO and the National IHR Focal Point.

UK is among the five WHO-named affected states. UKHSA monitoring travelers connected to the MV Hondius cluster; assessment of risk to the UK public is very low.

Argentina reports approximately 60–110 confirmed HPS cases per year, concentrated in southwestern Patagonia (Chubut, Río Negro, Neuquén) and the northwestern provinces. Argentina is the only country with confirmed person-to-person Andes transmission. Numbers shown reflect the Argentine Ministerio de Salud annual baseline; current weekly counts available from the boletín integrado.

Chile reports approximately 50–80 confirmed Andes hantavirus cases annually with seasonal peaks in summer (December–March). Aysén and Los Lagos consistently report the highest incidence per capita. Annual baseline; verify current week at ISP Chile.

Brazil reports approximately 80–150 confirmed HPS cases annually, with the highest incidence in southern and central-western states (Mato Grosso, Paraná, Rio Grande do Sul). Dominant strains vary by region.

Germany reports a strongly cyclical Puumala virus burden — peak years exceed 2,000 cases (e.g., 2012, 2017, 2019), trough years <300. Bavaria and Baden-Württemberg contribute the bulk. Cases are notifiable; verify current weekly counts at RKI SurvStat.

Finland reports the highest per-capita Puumala virus incidence in the world — approximately 1,000–3,000 confirmed cases per year (locally myyräkuume). Severe disease is rare; most patients recover with conservative management.

China reports more hantavirus cases than any other country — typically 10,000 to 20,000 confirmed HFRS cases annually depending on the cycle phase. Hantaan virus dominates in agricultural regions; Seoul virus in port cities. China uses a bivalent inactivated Hantaan/Seoul vaccine in high-incidence rural counties.

South Korea reports approximately 300–600 confirmed HFRS cases annually, concentrated in Gyeonggi, Gangwon, and Chungcheong provinces. The disease (Korean hemorrhagic fever) gave its name to the prototype Hantaan virus. KDCA uses inactivated Hantaan vaccine in high-risk military and rural populations.

Russia reports several thousand confirmed HFRS cases annually, dominated by Puumala virus in the Volga region (Bashkortostan being a notable focus) and Dobrava-Belgrade in the south.

MV Hondius is currently moored off Praia (Cabo Verde) under a WHO-coordinated maritime quarantine. Two evacuees airlifted off; no community transmission detected. Cabo Verde Ministry of Health and IHR Focal Point coordinating with WHO AFRO.

Sweden reports approximately 200–600 confirmed nephropathia epidemica (Puumala) cases per year, almost exclusively from the four northernmost counties. Cyclic 3-4 year peaks tracking bank vole populations.

Belgium reports 100–300 confirmed Puumala cases annually with a strong cyclic pattern. Wallonian forests (Ardennes) are the main exposure zone; outbreak years follow good acorn crops that drive vole populations.

France reports approximately 50–120 confirmed Puumala cases annually, concentrated in the Ardennes, Franche-Comté and Picardy regions. Notifiable disease since 2003.

Slovenia consistently reports 50–200 HFRS cases per year — high per-capita incidence. Mixed Dobrava (more severe) and Puumala epidemiology. Outbreak years aligned with neighbouring Balkan reservoirs.

Paraguay reports approximately 15–40 confirmed HPS cases annually, concentrated in the western Chaco. Laguna Negra virus dominant; carried by Calomys laucha (vesper mouse).

Uruguay reports approximately 5–20 confirmed HPS cases annually with substantial year-to-year variation. Cases tend to occur in agricultural workers and travelers to grain-storage facilities.

Panama reports 20–80 confirmed HPS cases annually, almost all from the Azuero Peninsula. Choclo virus (carried by Oligoryzomys fulvescens) gives Panama the highest per-capita HPS incidence in the Americas after Argentina/Chile, but with notably lower case-fatality.

Canada reports approximately 2–6 confirmed HPS cases annually, concentrated in Alberta, Saskatchewan, and British Columbia. PHAC notifiable since 1994.