Crossref · Wavefront propagation in a hyperbolic model of hantavirus infection · 1s agoCrossref · Could bradykinin pathway inhibition change the course of severe hantavirus disease? · 1s agoCrossref · Outbreak at Sea: The MV Hondius Hantavirus Cluster as a Sentinel for Global Pandemic Readiness · 1s agoCrossref · Microbe snapshots: Hantavirus (Sin Nombre) · 1s agoCrossref · Hantavirus on the rise: clinical, virological, immunological, and public health perspectives · 1s agoCrossref · Pregnancy and hantavirus infection: maternal, fetal, and neonatal outcomes − a systematic review · 1s agoCrossref · Emerging threat of hantavirus infection: Public health challenges during an international cruise ship outbreak · 1s agoCrossref · “Hantavirus at sea: Why cruise ships must be ready for animal-borne disease.” · 1s agoCrossref · Wavefront propagation in a hyperbolic model of hantavirus infection · 1s agoCrossref · Could bradykinin pathway inhibition change the course of severe hantavirus disease? · 1s agoCrossref · Outbreak at Sea: The MV Hondius Hantavirus Cluster as a Sentinel for Global Pandemic Readiness · 1s agoCrossref · Microbe snapshots: Hantavirus (Sin Nombre) · 1s agoCrossref · Hantavirus on the rise: clinical, virological, immunological, and public health perspectives · 1s agoCrossref · Pregnancy and hantavirus infection: maternal, fetal, and neonatal outcomes − a systematic review · 1s agoCrossref · Emerging threat of hantavirus infection: Public health challenges during an international cruise ship outbreak · 1s agoCrossref · “Hantavirus at sea: Why cruise ships must be ready for animal-borne disease.” · 1s ago
Strain · Southeastern United States

Bayou virus

Bayou virus is the second most common cause of hantavirus pulmonary syndrome in the United States after Sin Nombre.

HPSCFR ~33%8 reported cases (12 mo baseline)
CFR
33%
Cases (12mo)
8
Syndrome
HPS

Bayou virus is the second most common cause of hantavirus pulmonary syndrome in the United States after Sin Nombre. Reservoir: rice rat (Oryzomys palustris) in the southeastern US.

CASE FATALITY
33%
REPORTED CASES (12 MO)
8
SYNDROME
HPS
RESERVOIR
Oryzomys palustris (rice rat)

Active and recent clusters

  • United States · Four Corners endemic zone — 17 cases, 0 deaths (CFR 0%) · CDC NNDSS, 2026 MMWR week 17 (most recent published). United States reports approximately 15–40 confirmed HPS cases per year, concentrated in the Four Corners region (Sin Nombre virus). Numbers shown are the most recent CDC NNDSS Weekly publication.

Frequently asked

What does Bayou virus cause?

Bayou virus causes hantavirus pulmonary syndrome (HPS) with case fatality typically around 33%. Patients progress from a flu-like prodrome to acute respiratory distress.

Is Bayou virus contagious between people?

No documented person-to-person transmission. Bayou virus spreads via inhalation of aerosolized rodent excreta from its reservoir, Oryzomys palustris (rice rat).

Where does Bayou virus circulate?

Bayou virus circulates primarily in Southeastern United States. Its main reservoir is Oryzomys palustris (rice rat).

Related

Disclaimer. Strain pages are for general information. Diagnosis and treatment decisions must be made with a qualified clinician.