Crossref · Wavefront propagation in a hyperbolic model of hantavirus infection · 1s agoCrossref · Could bradykinin pathway inhibition change the course of severe hantavirus disease? · 1s agoCrossref · Driven magnetic 3D DNA walker coupled with CHA based on light-activatable hairpin: A dual-amplification strategy for ultrasensitive hantavirus RNA sensing · 1s agoCrossref · Artificial intelligence for chest imaging in hantavirus pulmonary syndrome: A review of practical considerations for rare-disease imaging · 1s agoCrossref · Outbreak at Sea: The MV Hondius Hantavirus Cluster as a Sentinel for Global Pandemic Readiness · 1s agoCrossref · Hantavirus Andean outbreak on an Antarctic cruise ship – confirmation from the frontline · 1s agoCrossref · Serologic Evidence of Hantavirus Exposure in Humans, Italy, 2004–2018 · 1s agoCrossref · Microbe snapshots: Hantavirus (Sin Nombre) · 1s agoCrossref · Wavefront propagation in a hyperbolic model of hantavirus infection · 1s agoCrossref · Could bradykinin pathway inhibition change the course of severe hantavirus disease? · 1s agoCrossref · Driven magnetic 3D DNA walker coupled with CHA based on light-activatable hairpin: A dual-amplification strategy for ultrasensitive hantavirus RNA sensing · 1s agoCrossref · Artificial intelligence for chest imaging in hantavirus pulmonary syndrome: A review of practical considerations for rare-disease imaging · 1s agoCrossref · Outbreak at Sea: The MV Hondius Hantavirus Cluster as a Sentinel for Global Pandemic Readiness · 1s agoCrossref · Hantavirus Andean outbreak on an Antarctic cruise ship – confirmation from the frontline · 1s agoCrossref · Serologic Evidence of Hantavirus Exposure in Humans, Italy, 2004–2018 · 1s agoCrossref · Microbe snapshots: Hantavirus (Sin Nombre) · 1s ago
Strain · East Asia

Hantaan virus

Hantaan virus is the prototype species, causing classic hemorrhagic fever with renal syndrome with up to ~10% case fatality in untreated cases.

HFRSCFR ~5%4,280 reported cases (12 mo baseline)
CFR
5%
Cases (12mo)
4,280
Syndrome
HFRS

Hantaan virus is the prototype species, causing classic hemorrhagic fever with renal syndrome with up to ~10% case fatality in untreated cases. Reservoir: striped field mouse (Apodemus agrarius). Highest case loads occur seasonally in China and Korea.

CASE FATALITY
5%
REPORTED CASES (12 MO)
4,280
SYNDROME
HFRS
RESERVOIR
Apodemus agrarius (striped field mouse)

Active and recent clusters

  • China · Shaanxi / Heilongjiang / Yunnan — 11000 cases, 110 deaths (CFR 1%) · Annual pattern; China CDC weekly bulletin. China reports more hantavirus cases than any other country — typically 10,000 to 20,000 confirmed HFRS cases annually depending on the cycle phase. Hantaan virus dominates in agricultural regions; Seoul virus in port cities. China uses a bivalent inactivated Hantaan/Seoul vaccine in high-incidence rural counties.
  • South Korea · Gyeonggi / Gangwon — 400 cases, 12 deaths (CFR 3%) · Annual pattern; KDCA infectious disease portal. South Korea reports approximately 300–600 confirmed HFRS cases annually, concentrated in Gyeonggi, Gangwon, and Chungcheong provinces. The disease (Korean hemorrhagic fever) gave its name to the prototype Hantaan virus. KDCA uses inactivated Hantaan vaccine in high-risk military and rural populations.

Frequently asked

What does Hantaan virus cause?

Hantaan virus causes hemorrhagic fever with renal syndrome (HFRS) with case fatality around 5%. The kidneys are the primary affected organ.

Is Hantaan virus contagious between people?

No documented person-to-person transmission. Hantaan virus spreads via inhalation of aerosolized rodent excreta from its reservoir, Apodemus agrarius (striped field mouse).

Where does Hantaan virus circulate?

Hantaan virus circulates primarily in East Asia. Its main reservoir is Apodemus agrarius (striped field mouse).

Related

Disclaimer. Strain pages are for general information. Diagnosis and treatment decisions must be made with a qualified clinician.