Sin Nombre virus
Sin Nombre virus is the dominant strain in the southwestern United States, causing hantavirus pulmonary syndrome.
Sin Nombre virus is the dominant strain in the southwestern United States, causing hantavirus pulmonary syndrome. Reservoir: deer mouse (Peromyscus maniculatus). Cases peak in spring after wet winters that increase rodent populations.
Active and recent clusters
- United States · Four Corners endemic zone — 17 cases, 0 deaths (CFR 0%) · CDC NNDSS, 2026 MMWR week 17 (most recent published). United States reports approximately 15–40 confirmed HPS cases per year, concentrated in the Four Corners region (Sin Nombre virus). Numbers shown are the most recent CDC NNDSS Weekly publication.
- Canada · western prairies — 4 cases, 1 deaths (CFR 25%) · Annual pattern; PHAC. Canada reports approximately 2–6 confirmed HPS cases annually, concentrated in Alberta, Saskatchewan, and British Columbia. PHAC notifiable since 1994.
Frequently asked
What does Sin Nombre virus cause?
Sin Nombre virus causes hantavirus pulmonary syndrome (HPS) with case fatality typically around 36%. Patients progress from a flu-like prodrome to acute respiratory distress.
Is Sin Nombre virus contagious between people?
No documented person-to-person transmission. Sin Nombre virus spreads via inhalation of aerosolized rodent excreta from its reservoir, Peromyscus maniculatus (deer mouse).
Where does Sin Nombre virus circulate?
Sin Nombre virus circulates primarily in North America. Its main reservoir is Peromyscus maniculatus (deer mouse).
Related
Disclaimer. Strain pages are for general information. Diagnosis and treatment decisions must be made with a qualified clinician.